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Drugs

Side Effects
Serious

Serious side effects are rare, but may include: heartbeat irregularities, chest pain, increased bronchial secretions. Some of these side effects may be relevant only to those who have a history of heart problems or respiratory conditions (see Disease Interactions).
Common

Excessive sweating, nausea, runny nose.
Less Common

Excessive salivation, weakness, sinusitis, upper respiratory infection, abdominal pain, urinary tract infection, coughing, vomiting, back pain, conjunctivitis, bronchitis, joint pain, fatigue, pain, insomnia, hot flushes.
Cevimeline Hydrochloride


Drug Class:
Cholinergic (muscarinic) agonist

Available OTC?: No

Available Generic?: No

Available In
Why Prescribed
How It Works
Range and Frequency
Onset of Effect
Duration of Action
Dietary Advice
Storage
Missed Dose
Stopping the Drug
Prolonged Use
Over 60
Driving and Hazardous Work
Alcohol
Pregnancy
Breast Feeding
Infants and Children
Special Concerns
Overdose Symptoms
What to Do
Drug Interactions
Food Interactions
Disease Interactions


Available In
Capsules

Why Prescribed
To treat symptoms of dry mouth in patients with Sjogren's Syndrome.

How It Works
Cevimeline stimulates the secretion of glands such as salivary and sweat glands and increases the tone of smooth muscle in the gastrointestinal and urinary tracts.

Range and Frequency
Adults: 30 mg 3 times a day.

Onset of Effect
Unknown.

Duration of Action
Unknown.

Dietary Advice
Cevimeline may be taken with or without food.

Storage
Store in a tightly sealed container away from heat, moisture, and direct light.

Missed Dose
Take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose.

Stopping the Drug
The decision to stop taking the drug should be made in consultation with your physician.

Prolonged Use
See your doctor regularly for tests and examinations if you must take this drug for a prolonged period.

Over 60
Adverse reactions may be more likely and more severe in older patients.

Driving and Hazardous Work
This drug can cause visual blurring, which may affect depth perception, night vision, and general vision. Do not drive or engage in hazardous work until you determine how the medicine affects you.

Alcohol
Avoid alcohol while taking this medication, as the diuretic effect of alcohol may aggravate your condition.

Pregnancy
No human tests have been done. However, discuss with your doctor the relative risks and benefits of using this drug while pregnant.

Breast Feeding
Cevimeline may pass into breast milk; caution is advised. Consult your doctor for advice on whether to discontinue nursing or discontinue the drug.

Infants and Children
The safety and effectiveness of this drug have not been established for children under the age of 18.

Special Concerns
Dehydration may result if you sweat excessively while taking cevimeline. Drink extra water and consult your doctor.

Overdose Symptoms
No cases of overdose have been reported.

What to Do
If you suspect an overdose or if someone takes a much larger dose than prescribed, call your doctor, emergency medical services (EMS), or the nearest poison control center immediately.

Drug Interactions
Consult your doctor for specific advice if you are taking a beta-blocker.

Food Interactions
No known interactions.

Disease Interactions
Do not take cevimeline if you have uncontrolled asthma or if you have an eye condition, such as acute iritis or narrow-angle glaucoma, which may be aggravated by the drug's tendency to cause the pupil's to constrict. The drug should not be used with caution in people with a history of kidney or gallbladder stones.

Date Published: 05/23/2005
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