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Drugs

Side Effects
Serious

No serious side effects have been reported.
Common

Dizziness, headache, fatigue.
Less Common

Chest pain; lightheadedness or fainting, especially when getting up quickly from a seated or lying position. Such symptoms are typically more common when you first take the medication, and generally diminish over time.
Alfuzosin Hydrochloride


Drug Class:
BPH therapy agent

Available OTC?: No

Available Generic?: No

Available In
Why Prescribed
How It Works
Range and Frequency
Onset of Effect
Duration of Action
Dietary Advice
Storage
Missed Dose
Stopping the Drug
Prolonged Use
Over 60
Driving and Hazardous Work
Alcohol
Pregnancy
Breast Feeding
Infants and Children
Special Concerns
Overdose Symptoms
What to Do
Drug Interactions
Food Interactions
Disease Interactions


Available In
Tablets

Why Prescribed
To ease urinary tract symptoms due to benign prostatic hyperplasia (BPH)—that is, noncancerous enlargement of the prostate gland, which is extremely common among men over the age of 50.

How It Works
Alfuzosin helps relax the muscles in the prostate gland and the opening of the bladder, improving the passage of urine.

Range and Frequency
10 mg a day.

Onset of Effect
Unknown.

Duration of Action
Unknown.

Dietary Advice
Take immediately after the same meal every day. Do not take on an empty stomach.

Storage
Store in a tightly sealed container away from heat, moisture, and direct light.

Missed Dose
Take it as soon as possible the same day. If it is the next day, skip the missed dose. Do not double the dose. Resume your regular dosage schedule.

Stopping the Drug
Take it as prescribed for the full treatment period, even if you feel better before the scheduled end of therapy.

Prolonged Use
Consult your doctor about the need for follow-up medical examinations and laboratory studies if you must take alfuzosin for a prolonged period.

Over 60
Older persons are generally more sensitive to alfuzosin and more likely to experience adverse side effects, especially when getting up from a lying or seated position. Rise slowly to minimize symptoms.

Driving and Hazardous Work
Alfuzosin may impair mental ability, causing drowsiness, lightheadedness, or dizziness, especially when you take the medication for the first time. Caution is advised; for 24 hours after the initial dose, avoid driving or other activities requiring mental alertness. Effects should diminish after several doses.

Alcohol
May increase effects of dizziness or fainting; drink in strict moderation, if at all.

Pregnancy
Alfuzosin is not indicated for use in women.

Breast Feeding
Alfuzosin is not indicated for use in women.

Infants and Children
Alfuzosin is not indicated for use in children.

Special Concerns
Do not crush, split, or chew tablets.

Overdose Symptoms
Extremely low blood pressure (hypotension), with accompanying fatigue, weakness, headache, palpitations, fainting, or dizziness.

What to Do
Call your doctor, emergency medical services (EMS), or the nearest poison control center immediately.

Drug Interactions
Do not take alfuzosin if you are taking antifungal drugs like ketoconazole or HIV drugs called protease inhibitors.

Food Interactions
None are expected.

Disease Interactions
Do not take alfuzosin if you have liver dysfunction. Consult your physician if you have kidney disease, severe heart disease, or chest pain caused by angina. Alfuzosin may aggravate these conditions.

Date Published: 05/23/2005
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