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Drugs

Side Effects
Serious

Difficulty swallowing; dizziness, lightheadedness, or fainting; flushing, redness, or change in color of skin; difficulty breathing, shortness of breath, tightness in the chest, or wheezing; sudden decrease in urine output; swelling of face, eyelids, or lips; black or tarry stools; unusual bleeding or bruising; yellow discoloration of the skin and eyes (indicating liver damage). Call your doctor immediately.
Common

Indigestion, nausea and vomiting, stomach pain.
Less Common

Sleeping difficulty, nervousness, irritability.
Acetaminophen/Aspirin/Caffeine


Drug Class:
Analgesic

Available OTC?: Yes

Available Generic?: No

Available In
Why Prescribed
How It Works
Range and Frequency
Onset of Effect
Duration of Action
Dietary Advice
Storage
Missed Dose
Stopping the Drug
Prolonged Use
Over 60
Driving and Hazardous Work
Alcohol
Pregnancy
Breast Feeding
Infants and Children
Special Concerns
Overdose Symptoms
What to Do
Drug Interactions
Food Interactions
Disease Interactions


Available In
Tablets, caplets, oral powder

Why Prescribed
For the temporary relief of mild to moderate pain associated with arthritis or migraine headache.

How It Works
Acetaminophen and aspirin both appear to interfere with the production of prostaglandins, naturally occurring substances in the body that cause inflammation and make nerves more sensitive to pain impulses. Caffeine is believed to enhance the effectiveness of pain relievers.

Range and Frequency
Because the amount of each of the components varies with different brands, consult your doctor for the appropriate dose. The following are general guidelines. Adults and teenagers-- Tablets and caplets: 1 to 2 tablets or caplets every three to six hours, as needed and depending on the strength of the product. Do not take more than eight pills in a 24-hour period. If migraine pain persists for more than 48 hours or joint pain lasts for more than 10 days, stop taking the medication and call your doctor. Oral powder: 1 packet of powder followed immediately by a full glass of water every six hours. Children-- Tablets and caplets: Consult your pediatrician. Children should not take more than five pills in a 24-hour period. Oral powder: Not recommended for children.

Onset of Effect
Unknown.

Duration of Action
Unknown.

Dietary Advice
Should be taken with food or a full glass of water to minimize stomach upset.

Storage
Store in a tightly sealed container away from heat, moisture, and direct light.

Missed Dose
Skip the missed dose and then resume your regular dosage schedule. Do not double the next dose.

Stopping the Drug
You may stop taking the drug whenever you choose.

Prolonged Use
This combination is indicated for short-term use only. Side effects are more likely with prolonged use.

Over 60
Adverse reactions may be more likely and more severe.

Driving and Hazardous Work
May cause drowsiness or vision difficulties.

Alcohol
Do not consume more than two alcohol-containing beverages a day.

Pregnancy
Discuss with your doctor the relative risks and benefits of using this drug while pregnant. This drug should not be used during the last three months of pregnancy.

Breast Feeding
This drug may pass into breast milk; consult your doctor for specific advice.

Infants and Children
Consult your pediatrician. This drug should not be taken by children under 16, since the aspirin component may cause a very rare but life-threatening condition known as Reye's syndrome.

Special Concerns
Be sure your doctor knows you are taking this medication; it can interfere with the results of some blood and urine tests. Patients allergic to aspirin should not take this medication.

Overdose Symptoms
Nausea and vomiting, disorientation, seizures, rapid breathing, ringing or buzzing in the ears, fever, appetite loss, abdominal pain, excessive sweating, drowsiness or exhaustion, stomach tenderness, heartbeat irregularities, yellow discoloration of the skin and eyes, agitation, anxiety, excitement, restlessness, delirium.

What to Do
Call your doctor, emergency medical services (EMS), or the nearest poison control center immediately.

Drug Interactions
Consult your doctor before taking this drug if you are currently taking any of the following: blood pressure medication, gout or arthritis drugs, anticoagulants such as warfarin, antidiabetic agents, steroids, seizure medication, NSAIDs, barbiturates, nicotine, zidovudine (AZT), isoniazid, any central nervous system stimulant, a MAO inhibitor, amantadine, over-the-counter cold and allergy medications, or asthma medicine.

Food Interactions
Do not drink large amounts of caffeine-containing beverages like coffee, tea, cola, cocoa, or chocolate milk.

Disease Interactions
Consult your doctor if you have liver or kidney disease, diabetes mellitus, phenylketonuria, a history of alcohol abuse, asthma, a bleeding disorder, congestive heart failure, gout, hemophilia, high blood pressure, thyroid disease, a peptic ulcer, anxiety, panic attacks, agoraphobia, or insomnia.

Date Published: 04/13/2005
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