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Drugs

Side Effects
Serious

No serious side effects have been reported to be directly associated with the use of buspirone.
Common

Dizziness or lightheadedness, nausea, paradoxical increase in nervousness or excitability, restlessness, headache.
Less Common

Blurred vision, impaired ability to concentrate, drowsiness, dry mouth, difficulty sleeping, muscle cramps or spasms, fatigue or weakness, ringing in the ears, dreams that are unusual, disturbing, or vivid.
Buspirone Hydrochloride


Drug Class:
Antianxiety drug

Available OTC?: No

Available Generic?: No

BuSpar 5 mg
(Mead Johnson)
Available In
Why Prescribed
How It Works
Range and Frequency
Onset of Effect
Duration of Action
Dietary Advice
Storage
Missed Dose
Stopping the Drug
Prolonged Use
Over 60
Driving and Hazardous Work
Alcohol
Pregnancy
Breast Feeding
Infants and Children
Special Concerns
Overdose Symptoms
What to Do
Drug Interactions
Food Interactions
Disease Interactions


Available In
Tablets

Why Prescribed
To treat anxiety.

How It Works
Buspirone affects the activity of specific brain chemicals (dopamine and especially serotonin) that are profoundly linked to mood, emotions, and mental state. Unlike many other medications used to treat anxiety disorders, buspirone has no muscle relaxant or sedative effects, and does not appear to lead to physical dependence.

Range and Frequency
To start, 5 mg, 3 times per day (for a total of 15 mg a day). Can be increased to 60 mg a day, taken in divided doses every 6 to 8 hours.

Onset of Effect
May take 1 to 2 weeks to attain the full therapeutic benefit of buspirone.

Duration of Action
8 hours or more.

Dietary Advice
No special restrictions.

Storage
Store in a tightly sealed container away from heat, moisture, and direct light.

Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time for your next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose.

Stopping the Drug
The decision to stop taking buspirone should be made in consultation with your physician.

Prolonged Use
No known problems.

Over 60
Adverse side effects and reactions may be more common and more severe in older patients.

Driving and Hazardous Work
The use of buspirone may impair your ability to drive or perform hazardous tasks safely. The danger increases if you drink alcohol or take other medications that can affect alertness, such as antihistamines, painkillers, or mind-altering drugs.

Alcohol
Avoid alcohol while using this medication.

Pregnancy
No problems are expected, but adequate studies of buspirone use during pregnancy have not been done. Consult your doctor if you are pregnant or plan to become pregnant.

Breast Feeding
Buspirone can pass into breast milk. Avoid taking it if possible or refrain from breast feeding.

Infants and Children
The safety and effectiveness of buspirone have not been established for anyone under the age of 18.

Special Concerns
Before you undergo surgery requiring anesthesia, be sure to notify the surgeon that you take buspirone.

Overdose Symptoms
Severe drowsiness, dizziness, nausea and vomiting, constricted (pinpoint) pupils.

What to Do
Call your doctor, emergency medical services (EMS), or the nearest poison control center immediately.

Drug Interactions
Other drugs may interact with buspirone. Consult your doctor for specific advice if you take any of the following: antihistamines, barbiturates, MAO inhibitors, muscle relaxants, narcotics, sedatives, or other tranquilizers.

Food Interactions
None expected.

Disease Interactions
Use of buspirone may cause complications in patients with liver or kidney disease, since these organs work together to remove the medication from the body.

Date Published: 04/13/2005
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