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Drugs

Side Effects
Serious

Yellow-tinged eyes or skin, skin rash or hives, eye pain, unusual bruising or bleeding, sore throat and fever. Call your doctor immediately.
Common

Constipation; dry mouth, nose, skin, or throat; decreased sweating; dizziness; drowsiness.
Less Common

Loss of memory, difficult urination, blurred vision, nausea or vomiting, bloated feeling, unusual weakness or tiredness, difficulty swallowing, decreased flow of breast milk.
Atropine Sulfate/Scopolamine Hydrobromide/ Hyoscyamine Sulfate/Phenobarbital


Drug Class:
Anticholinergic; antispasmodic

Available OTC?: No

Available Generic?: Yes

Available In
Why Prescribed
How It Works
Range and Frequency
Onset of Effect
Duration of Action
Dietary Advice
Storage
Missed Dose
Stopping the Drug
Prolonged Use
Over 60
Driving and Hazardous Work
Alcohol
Pregnancy
Breast Feeding
Infants and Children
Overdose Symptoms
What to Do
Drug Interactions
Food Interactions
Disease Interactions


Available In
Tablets, elixir, capsules, extended-release tablets

Why Prescribed
To relieve symptoms of irritable bowel syndrome, peptic and duodenal ulcers, and gastrointestinal cramps.

How It Works
Acetylcholine is a naturally occurring chemical in the body that is involved in the activity of nerves, muscles, glands, and other physiological processes. This drug interferes with the action of acetylcholine, leading to a variety of effects including the drying of secretions (saliva, perspiration), relief of muscle spasms in the intestines, and changing the size of the pupils.

Range and Frequency
Capsules or tablets-- Adults and teenagers: 1 or 2 capsules, 2 to 4 times a day. Children ages 2 to 12: 1/2 to 1 chewable tablet, 3 or 4 times a day. Elixir-- Adults: 5 to 10 ml, 3 to 4 times a day. Children: 0.5 to 7.5 ml every 4 to 6 hours. Extended-release tablets-- Adults and teenagers: 1 tablet every 8 to 12 hours. Children: Not recommended for use in patients under the age of 13.

Onset of Effect
Unknown.

Duration of Action
Unknown.

Dietary Advice
Take this medication 30 to 60 minutes before meals unless your doctor orders otherwise.

Storage
Store in a tightly sealed container away from heat, moisture, and direct light. Keep the liquid form refrigerated, but do not allow it to freeze.

Missed Dose
Take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose.

Stopping the Drug
The decision to stop taking the drug should be made by your doctor.

Prolonged Use
No special problems are expected.

Over 60
Adverse reactions may be more likely and more severe in older patients.

Driving and Hazardous Work
Do not drive or engage in hazardous work until you determine how the medicine affects you.

Alcohol
Avoid alcohol when using this medication.

Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant before taking this medicine.

Breast Feeding
This drug may pass into breast milk; caution is advised. Consult your doctor for advice.

Infants and Children
The drug should not be prescribed for children under age two. Adverse reactions may be more likely and more severe in infants and young children, especially those suffering from brain damage or spastic paralysis.

Overdose Symptoms
Nausea, vomiting, headache, blurred vision, dilated pupils, weak pulse, fever, hallucinations, seizures, unconsciousness, confusion, dry skin and mouth.

What to Do
Call your doctor, emergency medical services (EMS), or the nearest poison control center immediately.

Drug Interactions
Other drugs may interact with this medication. Consult your doctor for specific advice if you are taking an anticholinergic (such as belladonna), an adrenocorticoid, an antacid, an antidiarrheal medicine containing kaolin or attapulgite, ketoconazole, an anticoagulant (blood thinner), central nervous system depressants (such as antihistamines, cold medicines, sleep aids, or tranquilizers), an MAO inhibitor, haloperidol, or potassium chloride.

Food Interactions
No known food interactions.

Disease Interactions
Caution is advised when taking this drug. Consult your doctor if you have any of the following: a nerve disorder, asthma or other lung problems, an enlarged prostate, severe and continuing dry mouth, liver disease, kidney disease, Down's syndrome, intestinal blockage or other intestinal problems, an overactive thyroid gland, heart disease, high blood pressure, glaucoma, or ulcerative colitis.

Date Published: 04/13/2005
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