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Drugs

Side Effects
Serious

Vaginal itching, burning, discharge, or irritation not present prior to treatment. Call your doctor as soon as possible.
Common

No common side effects are associated with the use of butoconazole.
Less Common

Headache, stomach cramps or pain, irritation or burning of sexual partner's penis.
Butoconazole Nitrate


Drug Class:
Antifungal

Available OTC?: Yes

Available Generic?: No

Available In
Why Prescribed
How It Works
Range and Frequency
Onset of Effect
Duration of Action
Dietary Advice
Storage
Missed Dose
Stopping the Drug
Prolonged Use
Over 60
Driving and Hazardous Work
Alcohol
Pregnancy
Breast Feeding
Infants and Children
Special Concerns
Overdose Symptoms
What to Do
Drug Interactions
Food Interactions
Disease Interactions


Available In
Vaginal cream

Why Prescribed
To treat fungal (yeast) infections of the vagina.

How It Works
Butoconazole prevents fungal organisms from producing vital substances required for growth and function. This drug is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.

Range and Frequency
Nonpregnant women and teenagers: 5 g (1 applicatorful) of cream inserted with an applicator into the vagina at bedtime for 3 consecutive days. Pregnant women and teenagers: After third month, 5 g (1 applicatorful) of cream inserted with an applicator into the vagina at bedtime for 6 consecutive days.

Onset of Effect
Unknown.

Duration of Action
Unknown.

Dietary Advice
Butoconazole can be applied without regard to diet.

Storage
Store in a tightly sealed container away from heat, moisture, and direct light. Do not allow it to freeze.

Missed Dose
Insert it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule.

Stopping the Drug
Take the medicine as directed for the full treatment period, even if you begin to feel better before the scheduled end of therapy. Recurrence of the infection is likely if you stop before the full treatment period is complete.

Prolonged Use
Butoconazole is generally prescribed for short-term therapy (3 to 6 days).

Over 60
No special problems are expected.

Driving and Hazardous Work
The use of butoconazole should not impair your ability to perform such tasks safely.

Alcohol
No special precautions are necessary.

Pregnancy
Studies on the use of butoconazole during the first 3 months (trimester) of pregnancy have not been done. No adverse effects while using it during the second or third trimesters have been reported.

Breast Feeding
No problems are expected. Consult your doctor about using this medicine while nursing.

Infants and Children
Studies on the use of butoconazole in children have not been done. Consult your pediatrician for specific advice.

Special Concerns
The drug may be used with oral contraceptives and antibiotic therapy. Sanitary napkins should be used to prevent staining of clothing. The affected area should be kept cool and dry. The patient should wear loose-fitting cotton clothing and freshly laundered cotton underwear or pantyhose with a cotton crotch. Avoid underwear made from nonventilating materials. Do not sit for a long time in a wet bathing suit. Avoid feminine hygiene sprays. Wash daily with unscented soap and dry thoroughly with a clean towel. Tampons should not be used during therapy. The patient's sexual partner should wear a condom during intercourse and should consult a doctor if penile redness, itching, or discomfort occurs. Do not stop using this medicine during your menstrual period. After urination or a bowel movement, cleanse by wiping the area from front to back to prevent reinfection.

Overdose Symptoms
An overdose with butoconazole is unlikely.

What to Do
If someone should swallow a large amount of the medicine, call your doctor, emergency medical services (EMS), or the nearest poison control center immediately.

Drug Interactions
Tell your doctor if you are using any other vaginal prescription or over-the-counter medication.

Food Interactions
No food interactions have been reported.

Disease Interactions
No disease interactions have been reported.

Date Published: 04/13/2005
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